Estimados:
Les copio un fragmento de la Opinión de la Comisión Nacional Técnica de Bioseguridad del Brasil sobre el estudio de Seralini. Hace un momento les envie un comunicado similar de Health Canada. Como podrán apreciar esta Opinión se hizo a pedido del Ministerio de RREE brasileño.
Un ejemplo más de como en un país moderno el Estado, con rápidos reflejos, toma la iniciativa de tranquilizar a la población (como debe ser). En nuestro país NO se oye padre. Y para mejorar las cosas, el comunicado está en inglés como para que todo el mundo lo pueda entender. ¿Aquí harían lo mismo?
Saludos
Luis
PD. En archivo adjunto el documento con la Opinión completa.
CONSIDERED OPINION
The President of the Brazilian National Technical Commission on Biosafety - CTNBio, in response to the demand of the Ministry of Foreign Affairs, appointed a committee comprised of four distinguished researchers who evaluated the work of Séralini and his collaborators in prior publication on the journal Food and Chemical Toxicology, available on the website:
The President of the Brazilian National Technical Commission on Biosafety - CTNBio, in response to the demand of the Ministry of Foreign Affairs, appointed a committee comprised of four distinguished researchers who evaluated the work of Séralini and his collaborators in prior publication on the journal Food and Chemical Toxicology, available on the website:
http://ac.els-cdn.com/S0278691512005637/1-s2.0-S0278691512005637-main.pdf?_tid=bdde0922-2296-11e2-ada7-00000aab0f6c&acdnat=1351604340_c8d8f6b6fbeeec91e0ef4b1ca2444c8f .
The result of this evaluation is below:
Document evaluated
Séralini GE, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M, Hennequin D, de Vendômois JS. Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food Chem Toxicol. 2012 Sep 11.
Document evaluated
Séralini GE, Clair E, Mesnage R, Gress S, Defarge N, Malatesta M, Hennequin D, de Vendômois JS. Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Food Chem Toxicol. 2012 Sep 11.
pii:S0278-6915(12)00563-7. doi: 10.1016/j.fct.2012.08.005
Reviewers
Prof. Dr. José Fernando Garcia – School of Veterinary Medicine, São Paulo State
University Júlio de Mesquita Filho, Araçatuba, São Paulo
Prof. Dr. José Fernando Garcia – School of Veterinary Medicine, São Paulo State
University Júlio de Mesquita Filho, Araçatuba, São Paulo
Prof. Dr. Fernando Salvador Moreno – School of Pharmaceutical Sciences, Department
of Food and Experimental Nutrition, University of São Paulo, São Paulo, SP
of Food and Experimental Nutrition, University of São Paulo, São Paulo, SP
Professor. Dr. Nance Beyer Nardi - Stem Cell and Tissue Engineering Laboratory,
Lutheran University of Brazil, Canoas, RS
Summary
In an overall assessment, this study represents a strong commitment to assess the consequences of a diet with genetically modified (GM) plants, exposed or not to the herbicide to which they are resistant, as well as with the herbicide itself, to rats after a long-term treatment. Results generated could potentially bring valuable information
about the issue raised by the authors, however, the study completely fails to reach such purposes, due the following main reasons:
(1) The rat strain was poorly selected for the study, inasmuch as it is known that Sprague-Dawley rats develop tumors spontaneously in greater frequency than other strain (Keenam et al., 1979). The choice of another strain would have given greater consistency and reliability to the set of results of the study.
(2) Results are dramatically described and illustrated in a non-conventional fashion, leading to a relationship between feeding on GM plants and higher mortality or appearance of tumors, without, however, presenting numerical data in most analyzes, or statistical analyses that inform the level of significance of the data presented in a general way. A study of the document shows that the expression "statistic" appears only twice: in item 2.6, "Statistical analysis" in Materials and Methods; and in item 3.3 (Results, biochemical analyses), in the phrase "For biochemical measurements in rats, statistical analysis". This confirms that data presented as regards biochemical parameters were the only results submitted to statistical analysis, even so, rather unclear.
(3) Other points recommend caution with respect to the study, such as: Lack of a definition of the control maize lineage, described only as "closest isogenic maize" (Table 1); similar results are observed with GM maize treated or not with the herbicide and with the herbicide itself, without dose-effect relation; the number of animals per group
is very small (10 males and 10 females), particularly considering specific sex differences; for several of the results, groups "treated" (n=90) are compared with "controls" (n=10) for each sex, while control and experimental groups should have similar sample size.
is very small (10 males and 10 females), particularly considering specific sex differences; for several of the results, groups "treated" (n=90) are compared with "controls" (n=10) for each sex, while control and experimental groups should have similar sample size.
Finally, the review of the study indicates that based on the results presented it is not possible to establish any conclusions about the long-term effect of feeding on GM maize, treated or not with the respective herbicide, in rats. To this end, the findings should be described more accurately and submitted to a consistent statistical evaluation.
Therefore, this opinion indicates the main technical limitations, which invalidate the findings presented by the authors.
Therefore, this opinion indicates the main technical limitations, which invalidate the findings presented by the authors.
Luis De Stefano Beltrán, Ph.D.
Universidad Peruana Cayetano Heredia
Av Honorio Delgado 430
Lima 31, Perú
E-mail: luis.destefano@upch.pe
Skype: ludes1982
Twitter: @LuisDeStefano
Universidad Peruana Cayetano Heredia
Av Honorio Delgado 430
Lima 31, Perú
E-mail: luis.destefano@upch.pe
Skype: ludes1982
Twitter: @LuisDeStefano
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